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The page below is a sample from the LabCE course Biochemical Markers of Osteoporosis. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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FRAX (WHO Fracture Risk Assessment Tool)

One of the screening tools used to determine risk of osteoporosis is the FRAX tool. It has been developed by World Health Organization (WHO) to evaluate fracture risk of patients. It is based on individual patient models that integrate the risks associated with clinical risk factors as well as bone mineral density (BMD) at the femoral neck. It takes into consideration height, weight, previous fracture history, medications taken, as well as lifestyle choices such as smoking and alcohol intake.
The FRAX algorithms give the 10-year probability of fracture. The output is a 10-year probability of hip fracture and the 10-year probability of a major osteoporotic fracture (clinical spine, forearm, hip, or shoulder fracture).