Red Cell Disorders: Peripheral Blood Clues to Nonneoplastic Conditions (Online CE Course)
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This collection of informative case studies covers many current topics in red cell disorders. Topics include macrocytosis, intracellular RBC inclusions, echinocytes and acanthocytes, schistocytes, ovalocytes, and rouleaux. Numerous high-quality photomicrographs and real-life situations help ensure learning and retaining needed information.
Continuing Education Credits
- P.A.C.E.® Contact Hours (acceptable for AMT, ASCP, and state recertification): 3 hour(s)
- Florida Board of Clinical Laboratory Science CE - General (Hematology): 3 hour(s)
- Review normal and abnormal red blood cell morphologies.
- Recall the criteria for performing and reporting peripheral blood smear reviews.
- Demonstrate ability to evaluate red blood cell size, shape, and staining characteristics.
- Correlate observations of key red blood cell abnormalities on peripheral smears with associated clinical conditions.
- Recognize, via case studies, peripheral smear evaluations for red blood cell morphology and their clinical implications.
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- Introduction to Red Blood Cell Morphology
- Normal Red Blood Cell Morphology
- Normal Red Blood Cell (RBC) Morphology
- Evaluating Initial Red Blood Cell (RBC) Morphology
- Criteria for Peripheral Blood Smear Review
- The Peripheral Smear: Reviewing Red Blood Cell Morphology
- Introduction to Red Blood Cell Morphology Reporting
- Guidelines for Reporting Red Blood Cell Morphology
- This oil immersion field (1000x) is representative of the peripheral blood smear. Which report is the most appropriate for documentation of the findin...
- Abnormal Red Blood Cell Morphology Review
- Red Cell Morphology Reference Tables
- Size Variations in Red Blood Cells
- Anisocytosis Reference Table
- Variations in Hemoglobin Content
- Hemoglobin Content Reference Table
- Shape Variations in Red Blood Cells
- Poikilocytosis Review Table
- Abnormal Red Blood Cell Distribution
- Rouleaux and Agglutination
- Dimorphic (Double Cell) Population
- Case Studies in Red Blood Cell Nonneoplastic Conditions
- Introduction to Red Blood Cell Nonneoplastic Conditions Case Studies
- Hemolytic Conditions with Spherocytosis
- A 12-year-old child presents with jaundice and scleral icterus. The image to the right captures a representative section of the peripheral blood smear...
- Case continued:Which hematologic condition could be associated with the findings shown in these images?
- A known case of hemolytic disease of the newborn (HDN) is presented in the image on the right. Many different cellular morophologies are present. Apar...
- A 49-year-old male with pneumonia was treated with high-dose intravenous penicillin. He became jaundiced with yellow sclera. The image on the right is...
- Macrocytosis-Associated Conditions
- The complete blood count was obtained from a patient recently admitted to the emergency room. The red blood cell indices obtained revealed an MCV of 1...
- Conditions suggested by the macrocytes and the neutrophil in the photograph to the right include which of the following?
- Intracellular RBC Inclusions
- The RBC inclusions shown in the photograph represent which of the following?
- The peripheral blood smear represented by the image on the right was submitted for hematologic review. The identification of the RBC inclusions shown ...
- By utilizing a Prussian Blue stain, which of the following red blood cell inclusions would be identifiable if present? Note: Upper image = Wright-Giem...
- A ten-year-old boy came to a physician's attention because of recent jaundice and icteric sclerae after taking the medication Primaquine before a trip...
- Dimorphic Red Blood Cell Populations
- A blood smear represented by the photograph was submitted for hematologic review. Based on the erythrocyte morphology and the accompanying histogram, ...
- Target cells and Sickle Cells
- Hemoglobin E (Hb E) and HbE/Beta Thalassemia
- Case Study The image on the right is representative of the peripheral blood smear from a five-month-old immigrant from Asia. Her mother was concerned ...
- A peripheral smear with red blood cells photographed in a typical field was submitted for review. Which of the following conditions might be eliminate...
- A CBC performed on a 10-year-old African-American male who was brought to the emergency department with rapid, shallow breathing and fever provided th...
- Sickle cells along with target cells, as shown in this image, confirm a diagnosis of sickle cell disease (HbSS).
- Echinocytes and Acanthocytes
- The erythrocyte at the tip of the arrow in the image to the right is an echinocycte (burr cell).
- The peripheral blood picture shown in the image below is most consistent with an artifact of smear preparation.
- An isolated acanthocyte is most likely of little importance on an otherwise normochromic, normocytic peripheral blood smear.
- Schistocytes, Bite Cells, and Teardrop Cells
- The presence of erythrocytes with altered morphology (as indicated by the arrows in the image to the right) has a close association with each of the f...
- Which of the following conditions is associated with the defective erythrocytes that are indicated by the arrows in this image?
- The cells marked by blue arrows in the image below are associated with all of the following conditions except:
- A 5-year-old girl was brought to the emergency department with bloody diarrhea and severe abdominal pain. A complete blood count produced these result...
- Ovalocytes, Elliptocytes and Stomatocytes
- A teenage boy is visiting his doctor uder the suspicion of a viral illness. He has always been relatively healthy without many illness-related complai...
- Rouleaux and Erythrocyte Agglutination
- The arrangement of erythrocytes on this peripheral blood smear can be associated with each of the following conditions except:
- The arrangement of the erythrocytes in this peripheral smear should be reported out as rouleaux formation.
- Multiple Erythrocyte Abnormalities
- Case History
- Splenectomy Morphologies
- Poikylocytosis and Basophilic Stippling
Appreciation is expressed to Ms. Bette Jamison, MT (ASCP); Ms. Annie Elrod, MT (ASCP); John Ryder, MD; Peter Shen, MD; and other members of the University of Colorado Health Sciences Center Clinical Laboratory for their assistance in the acquisition of images and the proof reading of a large amount of textual material.
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